Monkeypox (Mpox) Diagnostic Testing and Vaccination Information

DuPage County Outpatient/Emergency Department Clinicians, Infectious Diseases Physicians, Hospital Infection Preventionists, and Laboratory Professionals,

Please read and reference the items in this toolkit for DuPage County Health Department’s (DCHD) current process for monkeypox (Mpox) virus diagnostic testing and resources, and share this information with your providers and colleagues as relevant. 

Commercial lab testing has become available (e.g., Labcorp, Mayo Clinic Laboratories, and Quest Diagnostics) and healthcare providers are encouraged to order testing for patients meeting clinical criteria through these commercial laboratories.

Patients should be told to isolate until results are known, and if positive, until all sores have healed, and a fresh layer of skin has formed. 

Providers are to collect two samples from a lesion using sterile dry polyester, rayon or Dacron swabs that should be readily available in most offices.

For monkeypox (Mpox) testing not performed at a commercial lab, public health approval for monkeypox (Mpox) testing is required before specimens may be sent to Illinois Department of Public Health (IDPH). 

DCHD monkeypox (Mpox) toolkit for providers


How does a provider obtain testing supplies for Monkeypox (Mpox)?

We created a document that outlines the testing process for healthcare providers: DuPage County Process for Monkeypox (Mpox) Virus Diagnostic Testing Toolkit (Updated 7/14/2022). You can reach out to the commercial lab from which you would be ordering monkeypox (Mpox) testing (e.g., Quest, Labcorp) to obtain supplies.


How do we protect our healthcare workers from being directly exposed?

CDC’s Infection Prevention and Control of Monkeypox in Healthcare Settings is a great resource that details patient placement, PPE, waste management, and environmental infection control measures that should be taken to prevent exposure and spread to healthcare professionals providing evaluation and care for a person suspected to have monkeypox (Mpox).


How does a provider obtain the JYNNEOS vaccine to vaccinate exposed healthcare workers and close contact patients? 

If you suspect or diagnose a monkeypox case, please contact our Communicable Disease & Epidemiology group for more information. They can be reached at 630-221-7553.

 If vaccine is indicated and available, we may be able to transfer the doses directly to your practice to be administered to the exposed healthcare workers and/or close contact patients. We would brief you on the process beforehand and ensure you are aware of all of the storing, handling, and reporting requirements.

DuPage County Health Department has received doses of the JYNNEOS monkeypox (Mpox) vaccine and is distributing vaccine to health care providers and administering vaccine to eligible individuals. Healthcare providers are able to request the vaccine for their patients through DCHD.

IDPH recommends vaccination for people who have been in close contact with people who have monkeypox (Mpox). Currently, people who may be eligible for vaccination include:

  • Anyone regardless of sex, gender, or sexual orientation who:
    • Had recent skin-to-skin contact or intimate contact with someone diagnosed with monkeypox (Mpox).
    • Exchanged goods or services for sex in the last six months.
    • Is living with HIV, especially persons with uncontrolled or advanced HIV disease. 
    • Is eligible or currently taking PrEP (pre-exposure prophylaxis) to help prevent infection with HIV.
  • Gay, bisexual and other men who have sex with men. transgender, or nonbinary people who in the past six months have had: 
    • a new diagnosis of one or more nationally reportable sexually transmitted diseases (i.e., acute HIV, chancroid, chlamydia, gonorrhea, or syphilis). 
    • More than one sexual partner. 
  • Sexual partners of people with the above risks. 
  • People who anticipate experiencing the above risks. 

Eligible individuals can schedule a vaccination appointment with DCHD by calling 630-682-7400.

How does a provider obtain TPOXX for a patient who has been diagnosed with monkeypox (Mpox)?

If you are treating a person with monkeypox (Mpox) who resides in DuPage County and would like to request antiviral treatment (tecovirimat or TPOXX) for them, please contact DuPage County Health Department by phone, during regular hours please contact DCHD at (630) 221-7553 or after hours at (630) 682-7400 and request to speak with the Communicable Disease and Epidemiology staff member on call. We have a limited supply on hand and can request additional courses through the CDC, as needed. 

Last Updated 11/30/2022